0
0
Sugar has a wide variety of applications in the pharmaceutical business due to its unique and multifunctional properties. It is extensively used as an excipient in the pharmaceutical industry. As a dormant component, it acts as the dosage vehicle for an active medicament, serving roles ranging from imparting bulk and consistency to tablets to make pleasant texture and flavour medicines. This is commonly done with pharma-grade sucrose or inverted sugar syrup. Sugar that is to be employed in the pharmaceutical sector requires pharmacopeia authorisation.
Sucrose: Sucrose is a non-reducing crystalline disaccharide composed of glucose and fructose is found in various plants. It is primarily derived as regular sugar from sugarcane and sugar beets. High-purity low endotoxin (HPLE) Sucrose is utilised in the biopharmaceutical sector to stabilise proteins, lipids, and carbohydrates during the formulation and freeze/thaw lifecycle of therapeutics. It is also often used as a cryopreservative and media enhancer in a broad range of cell-based bioprocesses. Some of the Pharmaceutical Advantages of Sucrose include-
- Stabilization of monoclonal antibodies (mAbs)
- Supplemental media
- Preservation of stem cells
- Vaccines stabilisation
- Stabilization of antibody-drug conjugates (ADCs)
- Stabilization of peptides
Invert Sugar: Invert sugar is synthesized via hydrolysis, which involves diluting sucrose with water and heating it until the molecular bonds between glucose and fructose dissolve. While pharmaceutical applications that formerly relied on sucrose are shifting to alternatives, demand for pharma grade invert sugar syrup is higher than ever. Some of the Pharmaceutical advantages of Invert Sugar include-
- Primary intravenous (IV’s) supplement, due to easy metabolism
- Controls the viscosity & the texture
- Specifications-based outcome.
- Taste enhancer
- Ideal for pediatric syrups as it provides instant energy and natural sweetness.
India has been a significant contributor to the recent increase in demand for pharma grade invert sugar syrup. A burgeoning middle class has boosted consumer knowledge and desire for medical care, compelling medicine producers to rely on external sugar distributors to meet customer demands. As a result, multiple new bulk industrial sugar production plants have sprouted up across India
What is Pharma Sugar?
Sucrose IP, often known as Pharma Sugar, possesses all of the characteristics that distinguish it as the highest quality pharma-grade sugar. Sucrose IP, unlike other sugars on the market, is not bleached with sulphur dioxide which makes it India’s sole sulphur-free sugar. Sucrose IP is a pharmaceutical-grade sugar that satisfies IP specifications r. (EU is a different pharmacopeia) Pharma sugar ‘Sucrose IP’ is a premium sugar made using a ‘phospho-flotation technique’ in combination with a double-stage ion-exchange column made of acrylic and styrene-based resins and under the tightest quality requirements. Pharma Sugar is extremely simple to use and store. . It is being packed in HDPE liners (placed inside the PP bags) to impart extra prevention from moisture and stored in air conditioned storages.
How Is Pharma Grade Sugar Tested, and What Accreditations Must It Receive?
Sugar brought in the pharmaceutical sector requires pharmacopeia authorisation. The European Pharmacopoeia (EP) is the legal and scientific standard against which all pharmaceutical goods manufactured and marketed in 38 European nations and over 100 countries across the world are assessed. It guarantees that standards are maintained at an exceedingly high level and that only the highest-quality items are created.
The British Pharmacopoeia (BP) runs concurrently with the EP. This has regulated quality standards for pharmaceutical and therapeutic products manufactured and utilized in the United Kingdom and over 100 other nations, mostly former Commonwealth countries, since 1864. All sugars used in this industry are allocated a British Pharmacopoeia Chemical Reference Substance (BPCRS) – a document that specifies the exact chemical structure that they must have to be approved for utilization.
Pharma Sugar at Triveni:
Triveni Group plays a pioneering role in the sugar industry. They are India’s second-largest sugar producer, with seven FSSC 22000 certified sugar facilities. Their factories are strategically positioned in the sugarcane-rich region of Uttar Pradesh. They manufacture a wide range of high-quality multi-grade (large, medium, small) crystal, refined, and pharmaceutical-grade sugar for usage in a multitude of sectors.
Triveni aims to maintain the highest product quality in all its sugar factories outfitted with cutting-edge technology and testing labs. Triveni Engineering’s Sabitgarh unit grade manufactures Pharma Sugar in full accordance with the IP and BP requirements and has I.P (Indian pharmacopeia) and B.P (British Pharmacopoeia) certifications, in addition to FSSC & HALAL. As a corollary, they can assure that the sugar being supplied to pharmaceutical clients are always of the utmost quality and are precisely customised as per their requirements. . Overall, this delivers good sugars that result in a consistent end product, which would be critical for fabricating in massive amounts. Moreover, the Triveni Pharma sweetener may be used by pharmaceutical companies that export drugs/formulations to countries that follow B.P certificates, in addition to the bulk of Indian pharma companies that follow IP regulations.
